BACKGROUND: Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and management of alloimmunization, delayed hemolytic transfusion reactions (DHTRs), and iron overload may improve outcomes. OBJECTIVE: Our objective was to develop …
BACKGROUND: Vitamin D (25(OH)D) deficiency has become an emerging public health problem due to its influence on skeletal and extraskeletal diseases. Bone health in patients with sickle cell disease (SCD) is especially compromised and they are more likely to have 25(OH)D deficiency than the general population. Despite this, there is little information on the efficacy …
“A team at De Montfort University (Professor Simon Dyson and Dr Maria Berghs) in the UK has recently completed a project looking at sickle cell, work and employment. The project has produced a Guide to Sickle Cell and Employment and produced a web-site with some further resources at http://sicklecellwork.dmu.ac.uk. …
