Month: July 2019

Resolution of Acute Priapism in Two Children with Sickle Cell Disease who Received Nitrous Oxide.

BACKGROUND: Nitrous oxide (N2O) is an inhalational medication with few side effects that has anxiolytic, amnestic, potent venodilatory and mild-to-moderate analgesic properties commonly used in the emergency department (ED) setting. Priapism is a serious complication of sickle cell disease (SCD) with few treatment options and an adverse impact on quality of life. Although a 50:50 …

Cure Sickle Cell Initiative Research Opportunity Announcement

The NHLBI is soliciting applications for the following research opportunity: “Analytical and/or Clinical Validation of Candidate Biomarkers for Curative Therapies in Sickle Cell Disease.” The proposed projects will develop and validate assays for biomarkers of clinical endpoints, to be used in clinical trials of genetic-based curative treatments for sickle cell disease. Applications are due July 31, …

Six essential updates for World Sickle Cell Day

World Sickle Cell Day is held every June 19. The observance — established by the United Nations — is designed to increase knowledge and understanding of sickle cell disease, as well as the challenges that patients, their families and their caregivers face. 1. HemOnc Today’s June 10 cover story focused on sickle cell disease, the …