Category: CURRENT SICKLE CELL NEWS

This category contains the current sickle cell anemia news.

Researchers tackle sickle cell disease with CRISPR-based gene editing

$1 million grant will advance personalized medicine using gene editing at ChristianaCare’s Gene Editing Institute Scientists at ChristianaCare’s Gene Editing Institute have received a $1 million grant from the Lisa Dean Moseley Foundation to develop a novel gene therapy for inherited blood disorders including sickle cell disease, offering hope to nearly 100,000 Americans suffering from …

Sickle cell maculopathy: prevalence, associations and impact on visual acuity

Abstract Aims: To investigate the prevalence of sickle cell maculopathy (SCM), associations with age, sex, genotype and proliferative sickle cell retinopathy (PSR) stage and the impact on visual acuity Methods: Age, sex and visual acuity were recorded and spectral domain OCT and ultra-widefield images of the macula and retina were reviewed for a consecutive series …

Emergence of gram-negative organisms as the cause of infections in patients with sickle cell disease

Abstract Background: Patients with sickle cell disease are at higher risk of infections with encapsulated bacteria due to immature immune responses and functional asplenia. We aimed to study our patient population for the emergence of gram-negative organisms other than Salmonella as the cause of osteomyelitis and document a vast decrease in Streptococcus pneumoniae bacteremia rates. …

Nonopioid Pharmacologic Treatments for Chronic Pain.

OBJECTIVES: To evaluate the effectiveness and comparative effectiveness of nonopioid pharmacologic agents in patients with specific types of chronic pain, considering effects on pain, function, quality of life, and adverse events.DATA SOURCES:Electronic databases (Ovid® MEDLINE®, Embase®, PsycINFO®, CINAHL®, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews) through September 10, 2019, reference …

Clarification on Pain Management Recommendations for Cancer and Sickle Cell Disease

Representatives from the National Comprehensive Cancer Network (NCCN), American Society for Clinical Oncology (ASCO), American Society of Hematology (ASH), CDC, FDA, and the authors of the JAMA Oncology article detailing the meeting convened to address the perceived variance among clinical practice guidelines for disease management in patients with cancer and those with sickle cell disease.1 Though there …

TIPS TO STAY SAFE

What are the symptoms of COVID-19? Common symptoms of COVID-19 begin up to 14 days after exposure. Presentation of illness ranges from asymptomatic/ mild symptoms to severe illness and mortality. The symptoms include: General symptoms Fever Headache Fatigue Generalized weakness *Usually accompanied by fever Respiratory symptoms Gastrointestinal symptoms Nausea Vomiting Abdominal Pain Diarrhea *Usually accompanied by …

COVID-19 AND SICKLE CELL

A Message from the President Dr. Jean Walrond Ph.D. The COVID-19 virus has brought to the forefront our once again that our mission is to educate our sickle cell anemia patients, families and stakeholders. Fortunately, we have been working hard to lay a foundation so we can provide our members with timely and important information …

Evaluation of the effectiveness of prophylactic oral vitamin D (cholecalciferol) in children with sickle cell disease

BACKGROUND: Vitamin D (25(OH)D) deficiency has become an emerging public health problem due to its influence on skeletal and extraskeletal diseases. Bone health in patients with sickle cell disease (SCD) is especially compromised and they are more likely to have 25(OH)D deficiency than the general population. Despite this, there is little information on the efficacy …

Press Release on New Born Screening in Alberta

June 19, 2019 Newborn screening now tests for sickle cell disease CALGARY – All babies in the province are now eligible for routine testing for sickle cell disease following an expansion to Alberta’s Newborn Metabolic Screening (NMS) program. Sickle cell disease causes red blood cells to have a crescent moon or sickle shape and become …

Home Feature Slider Run

Second Annual 3K Walk / Run Caribbean Heritage Sports Day at Rotary Challenger Park in Calgary September 8, 2018 Click Here for Full Details …