This category contains the current sickle cell anemia news.
The pain from a sickle cell crisis is one of the most devastating things I have felt. It is unpredictable and can eat away at you physically, spiritually, and mentally. The normal response to severe pain is to cure it or ease it, which usually involves taking some type of painkiller. But I’ve never felt comfortable taking …
Visual Abstract Patients with sickle cell disease (SCD) are at high risk of developing serious infections, therefore, understanding the impact that severe acute respiratory syndrome coronavirus 2 infection has on this population is important. We sought to identify factors associated with hospitalization and serious COVID-19 illness in children and adults with SCD. We established the …
$1 million grant will advance personalized medicine using gene editing at ChristianaCare’s Gene Editing Institute Scientists at ChristianaCare’s Gene Editing Institute have received a $1 million grant from the Lisa Dean Moseley Foundation to develop a novel gene therapy for inherited blood disorders including sickle cell disease, offering hope to nearly 100,000 Americans suffering from …
Abstract Aims: To investigate the prevalence of sickle cell maculopathy (SCM), associations with age, sex, genotype and proliferative sickle cell retinopathy (PSR) stage and the impact on visual acuity Methods: Age, sex and visual acuity were recorded and spectral domain OCT and ultra-widefield images of the macula and retina were reviewed for a consecutive series …
Abstract Background: Patients with sickle cell disease are at higher risk of infections with encapsulated bacteria due to immature immune responses and functional asplenia. We aimed to study our patient population for the emergence of gram-negative organisms other than Salmonella as the cause of osteomyelitis and document a vast decrease in Streptococcus pneumoniae bacteremia rates. …
OBJECTIVES: To evaluate the effectiveness and comparative effectiveness of nonopioid pharmacologic agents in patients with specific types of chronic pain, considering effects on pain, function, quality of life, and adverse events.DATA SOURCES:Electronic databases (Ovid® MEDLINE®, Embase®, PsycINFO®, CINAHL®, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews) through September 10, 2019, reference …
Representatives from the National Comprehensive Cancer Network (NCCN), American Society for Clinical Oncology (ASCO), American Society of Hematology (ASH), CDC, FDA, and the authors of the JAMA Oncology article detailing the meeting convened to address the perceived variance among clinical practice guidelines for disease management in patients with cancer and those with sickle cell disease.1 Though there …
What are the symptoms of COVID-19? Common symptoms of COVID-19 begin up to 14 days after exposure. Presentation of illness ranges from asymptomatic/ mild symptoms to severe illness and mortality. The symptoms include: General symptoms Fever Headache Fatigue Generalized weakness *Usually accompanied by fever Respiratory symptoms Nasal congestion Sore throat Cough dry or with sputum Coughing …
A Message from the President Dr. Jean Walrond Ph.D. The COVID-19 virus has brought to the forefront our once again that our mission is to educate our sickle cell anemia patients, families and stakeholders. Fortunately, we have been working hard to lay a foundation so we can provide our members with timely and important information …
BACKGROUND: Vitamin D (25(OH)D) deficiency has become an emerging public health problem due to its influence on skeletal and extraskeletal diseases. Bone health in patients with sickle cell disease (SCD) is especially compromised and they are more likely to have 25(OH)D deficiency than the general population. Despite this, there is little information on the efficacy …
